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Case No. 757
2026-07-01~2026-07-31
출제자 : 서배선
Hit : 363
| Period | 2026-07-01~2026-07-31 |
|---|---|
| Diagnosis | Germinoma |
| Gender |
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| Age | 27 |
| Clinical information | 27/M Chief complaint) Decreased concentration and difficulty understanding speech for 2–3 years. Generalized tonic-clonic seizure on 2025. What's your diagnosis? |
| Discussion | Intracranial germinomas typically arise in the pineal and neurohypophyseal regions. Approximately 5–10% occur in ectopic locations and tend to involve midline structures, particularly the basal ganglia, thalami, and diencephalon. Other reported sites include the corona radiata, temporal lobe, cerebellum, and medulla oblongata, with the corpus callosum being the least common location. Imaging findings include T2 hyperintensity, cystic changes, heterogeneous enhancement, and calcifications. References) Matsutani M, Sano K, Takakura K, Fujimaki T, Nakamura O, Funata N, Seto T. Primary intracranial germ cell tumors: a clinical analysis of 153 histologically verified cases. J Neurosurg. 1997 Mar;86(3):446-55. Shankar S, Wu X, Kalra VB, Huttner AJ, Malhotra A. Ectopic intracranial germinoma. J Clin Neurosci. 2016 Sep;31:192-5. |
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