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종결 Case No. 742 2026-01-01~2026-01-31
출제자 : 박상익 Hit : 431
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Period 2026-01-01~2026-01-31
Diagnosis Post-transplant lymphoproliferative disorder
Gender
  • M
  •  
  • F
Age 49
Clinical information A 49-year-old female patient with a history of pancreatic transplantation 14 years ago presented with complaints of disorientation.
What was the diagnosis?
Discussion CNS PTLD differs from typical primary CNS lymphoma in that it more frequently presents as multifocal lesions with ring or heterogeneous enhancement and a higher tendency for hemorrhage or necrosis, while primary CNS lymphoma usually shows solid, homogeneous enhancement. On diffusion imaging, PTLD may show diffusion restriction but with higher ADC values compared with diffusion restriction seen in conventional CNS lymphoma. CNS PTLD commonly shows punctate or peripheral susceptibility on SWI or GRE.

Reference
White ML, Moore DW, Zhang Y, et al. Primary central nervous system post-transplant lymphoproliferative disorders: the spectrum of imaging appearances and differential. Insights Imaging. 2019;10:46.
Correct answer

Correct Answer

  • 조서범 연세대학교 세브란스병원
  • 권오민 가톨릭대학교 여의도성모병원
  • 강예슬 연세대학교 용인세브란스병원
  • Murat Ulusoy GOP Avrasya Hospital Istanbul/TR

Semi-Correct Answer

  • 정하경 서울아산병원
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    Murat Ulusoy

    GOP Avrasya Hospital Istanbul/TR 2026-01-21 11:53:23
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