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종결 Case No. 729 2025-09-01~2025-09-30

출제자 : 주비오 Hit : 356

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Period	2025-09-01~2025-09-30
Diagnosis	Paraneoplastic syndrome associated with Anti-Yo antibody
Gender	M F
Age	47
Clinical information	F/47, Diagnosed with breast cancer in 2020, Normal genetic study for cerebellar ataxia What's your diagnosis?
Discussion	A paraneoplastic syndrome with anti-Yo antibodies is a rare immune-mediated disorder that causes subacute cerebellar degeneration. Anti-Yo antibody, also known as Purkinje cell cytoplasmic antibody type 1 (PCA-1), accounts for approximately half of all antibody-mediated paraneoplastic cerebellar degeneration cases and is most commonly associated with ovarian and breast cancers. Ref: Cureus. 2021 Dec 6;13(12):e20203. doi: 10.7759/cureus.20203
Correct answer	Correct Answer 김찬순 계명대학교 동산의료원 김신영 양산부산대학교병원 고지수 서울아산병원 윤정택 경희대학교병원 조서범 연세대학교 세브란스병원 이강휘 서울대학교병원 Murat Ulusoy GOP Avrasya Hospital Istanbul/Turkey 홍혁기 서울의료원 이진영 동국대학교 일산병원 류혜선 강동경희대학교병원 권오민 가톨릭대학교 여의도성모병원 조성찬 단국대학교병원 신동한 전북대학교병원 Semi-Correct Answer

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Murat Ulusoy

GOP Avrasya Hospital Istanbul/Turkey 2025-09-17 11:58:52

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