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Case No. 681
2024-03-01~2024-03-31
출제자 : 이지영
Hit : 419
| Period | 2024-03-01~2024-03-31 |
|---|---|
| Diagnosis | B-cell precusor acute lymphoblastic leukemia involvement |
| Gender |
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| Age | 41 |
| Clinical information | C.C) headache Underlying ALL |
| Discussion | Leukemia involvement in the brain -Leukemic cell infiltation of the meninges, parenchyma, bone marrow, orbit (optic nerve), and spine. -Intracranial involvement. meningeal disease intravascular tumor aggregates throughout the brain focal tumor masses -Myeloid lineage--> myeloid sarcoma (=chloroma= granulocytic sarcoma) : A solid extramedullary neoplasm composed of primitive myeloid cells, in patients with myeloproliferative disorders, especially in AML. -Lymphoid lineage--> leukemic infiltration/involvement MR: meningeal and nerve root enhancement thickening and abnormal enhancement of the optic nerve, retinal hemorrhage dura-based focal masses precontrast iso- to hyperdense T2-hyperintense, diffusion restriction marked homogeneous enhancement Parenchymal lesions - variable T1-iso, T2-hyperintense, perilesional edema, enhancement |
| Correct answer |
Correct AnswerSemi-Correct Answer |