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Case No. 668
2023-09-01~2023-09-30
출제자 : 박미나
Hit : 533
| Period | 2023-09-01~2023-09-30 |
|---|---|
| Diagnosis | Secondary hemochromatosis |
| Gender |
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| Age | 82 |
| Clinical information | 82세 남환 lung cancer staging 위해 시행한 MRI 이다. 2018년 myelodyplastic syndrome with multilineage dysplais로 진단받고 치료 받은 과거력이 있음. 진단은? |
| Discussion | Hemochromatosis refers to iron overload, which results from a hereditary/primary cause or from a metabolic/hematologic disorder. Hemochromatosis also occurred secondary to iron overload from blood transfusions for thalassemia. Organs commonly affected by hemochromatosis include the liver, heart, and endocrine glands. In the brain, iron deposition is typically seen at sites outside the blood-brain barrier, which include the pituitary gland, choroid plexus, pineal gland, and area postrema. Key Diagnostic Feature: Increased iron load will result in increased susceptibility. This can be seen on T2WI but still better on gradient-echo or susceptibility-weighted images. Thus, increased susceptibility involving the 4 p’s—the pituitary gland, choroid plexus, pineal gland, and area postrema—should suggest hemochromatosis. |
| Correct answer |
Correct AnswerSemi-Correct Answer |