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종결 Case No. 652 2023-04-01~2023-04-30
출제자 : 임영희 Hit : 431
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Period 2023-04-01~2023-04-30
Diagnosis epidermoid cyst
Clinical information 51/M
우측 청력 저하, 5개월 전
진단은?
Discussion
CSF-like mass, insinuates cisterns and encases neurovascular structures.
Lobulated, irregular, cauliflower-like mass
Intradural (90%), primarily in basal cisterns
Extradural (10%), skull and spine.


1. CT
Round/lobulated mass
> 95% hypodense, resembling CSF
10-25% contain calcifications
Rare variant = “dense” epidermoid
Usually non-enhancing, margin of cyst may show minimal enhancement.
May have bony erosion
2. MR
2-1. T1WI
Often (~ 75%) slightly hyperintense to CSF
Uncommonly hyperintense to brain (“white epidermoid”) due to high triglycerides and unsaturated fatty acids
Uncommonly hypointense to CSF (“black epidermoid”) ; Presence of solid crystal cholesterol and keratin, Lack of triglycerides and unsaturated fatty acids

2-2. T2WI
Often isointense (65%) to slightly hyperintense (35%) to CSF
Very rarely hypointense due to calcification, ↓ hydration, viscous secretions, and iron pigments

2-3. FLAIR; Usually does not completely null

2-4. DWI; Characteristic hyperintensity, ADC = brain parenchyma

2-5. T1WI C+
Usually none, though margin of cyst may show minimal enhancement (25%)
Enhancing tumor is sign of malignant degeneration

2-6. MRS: Resonances from lactate, No NAA, choline, or lipid


Reference
Diagnostic Imaging: Brain, 3rd Edition
Anne G Osborn & Miral D Jhaveri & Karen L. Salzman & A. James Barkovich
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  • 홍혁기 서울의료원
  • 송한림 예수병원
  • 김건희 양산부산대학교병원
  • 박혜주 순천향대학교 부천병원
  • 김신영 양산부산대학교병원
  • 김효진 가톨릭대학교 서울성모병원
  • 이진영 동국대학교 일산병원
  • 류혜선 강동경희대학교병원
  • 전차웅 가톨릭대학교 여의도성모병원
  • 홍성호 서울대학교병원

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