HOME > Weekly Case > Weekly Case
Weekly Case
종결
Case No. 643
2023-01-01~2023-01-31
출제자 : 서종현
Hit : 464
| Period | 2023-01-01~2023-01-31 |
|---|---|
| Diagnosis | EXTRANODAL NK/T CELL LYMPHOMA, NASAL TYPE |
| Gender |
|
| Age | 26 |
| Clinical information | 기저질환 없던 환자로 수개월 전부터 우측 얼굴이 부었다 안부었다 하는 양상이 반복되어 내원한 26세 남자 환자이다. 진단은? |
| Discussion | 1. Introduction Extranodal NK/T-cell lymphoma (ENKTL), nasal type, is commonly located in the upper respiratory tract, but involvement of other organs can be observed, particularly the skin, which is the second most usual site of this lymphoma after the nasal cavity and nasopharynx. Cutaneous ENKTL can be divided into two distinct subsets: primary cutaneous, that initially presents in the skin, or nasal ENKTL accompanied by secondary spread to the skin. Both forms are rare and are more prevalent in Asia, Central and South America. Epstein-Barr virus (EBV) is expressed in almost all cases of ENKTL, implying that it may play a pathogenic role. Extra-nasal ENKTL was first described in 1992 by Chan et al and this entity demonstrates many morphologic and immunophenotypic similarities to nasal ENKTL, thus the common designation “nasal-type” even for the extra-nasal forms. |
| Correct answer |
Correct AnswerSemi-Correct Answer |