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Case No. 640
2022-11-01~2022-11-30
출제자 : 김슬기
Hit : 780
| Period | 2022-11-01~2022-11-30 |
|---|---|
| Diagnosis | Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) |
| Gender |
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| Age | 26 |
| Clinical information | 26세 여자 C.C>Seizure (두차례, 2 months ago, 1 day ago) 진단은? |
| Discussion | 진단: Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) 고찰 • Pediatric type, low grade diffuse glioma in 2021 WHO brain tumor classification • First described in 2016 • Pathologic and genetic feature Oligodendroglioma-like cellular elements, calcification Strong CD34 immunopositivity Mutation of BRAF V600E gene and FGFR (fibroblast growth factor receptor) 2 and 3 Abnormal regulation of the MAPK oncogenic pathway • Radiologic feature Arises from cortex with temporal lobe predilection CT - hypodense mass with frequently calcification MRI -T2/FLAIR heterogeneous SI with salt and pepper (due to calcification and cyst), no diffusion restriction, slight or no enhancement |
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