| Period | 2022-02-01~2022-02-28 |
|---|---|
| Diagnosis | PML-IRIS |
| Gender |
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| Age | 72 |
| Clinical information | Question> F/72Y Symptom: Rapid cognitive impairment., Medical history: On steroid and immunosuppressive agent due to SLE 진단은? Images> axial DWI, axial ADC, axial T2WI,axial Gd_T1WI |
| Discussion | PML usually shows no mass effect or enhancement - HIV-associated PML (15%) natalizumab-associated PML (40%) - increasing enhancement, mass effect & edema attributable to immune reconstitution PML-IRIS (immune reconstitution inflammatory syndrome) - Hyperintense WM lesions: enlarge, become confluent, exert mass effect - patchy atypical enhancement |
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