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Weekly Case

종결 Case No. 617 2022-02-01~2022-02-28
출제자 : 조세진 Hit : 786
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Period 2022-02-01~2022-02-28
Diagnosis PML-IRIS
Gender
  • M
  •  
  • F
Age 72
Clinical information Question>
F/72Y
Symptom: Rapid cognitive impairment.,
Medical history: On steroid and immunosuppressive agent due to SLE

진단은?

Images> axial DWI, axial ADC, axial T2WI,axial Gd_T1WI
Discussion PML usually shows no mass effect or enhancement
- HIV-associated PML (15%) natalizumab-associated PML (40%)
- increasing enhancement, mass effect & edema attributable to
immune reconstitution
PML-IRIS (immune reconstitution inflammatory syndrome)
- Hyperintense WM lesions: enlarge, become confluent, exert mass effect
- patchy atypical enhancement
Correct answer

Correct Answer

  • 도윤아 분당서울대학교병원
  • 최규성 서울대학교병원
  • 김효영 고려대학교 안산병원
  • 이경훈 서울대학교병원

Semi-Correct Answer

  • 문경일 전남대학교병원
  • 조황희 ----
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