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Case No. 611
2021-12-01~2021-12-31
출제자 : 유인선
Hit : 744
| Period | 2021-12-01~2021-12-31 |
|---|---|
| Diagnosis | Solitary fibrous tumor |
| Gender |
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| Age | 65 |
| Clinical information | M/65 수주 전 우연히 발견한 이마 종괴 진단은? |
| Discussion | Solitary fibrous tumor 1) Introduction (SFT/HPC new entity SFT/HPC in 2016 WHO classification) CNS Solitary fibrous tumors (SFT) type • Generally benign (Grade I) • But, clinical behaviors were found to be unpredictable, with several reports of a malignant clinical course CNS Hemangiopericytoma (HPC) type • Aggressive mesenchymal tumor (pericyte origin) (grade II or III) • High propensity for local recurrence (>75% in 10 years) and extracranial metastasis • Majority of SFTs and HPCs in soft tissue share inversions at 12q13, fusing NAB2 & STAT6 genes 2) Imaging findings: • Almost always solitary, dura-based (narrowly), supratentorial or occipital • Solid ± cystic components, often lobulated, irregular border • Tendency to erode adjacent bone, no hyperostosis, no calcification • Intense enhancement (can be heterogeneous) with multiple flow voids & dural tail sign (Gr II > III, due to more rapid growth) |
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