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Case No. 609
2021-12-01~2021-12-31
출제자 : 유인선
Hit : 389
| Period | 2021-12-01~2021-12-31 |
|---|---|
| Diagnosis | Olfactory neuroblastoma |
| Gender |
|
| Age | 38 |
| Clinical information | M/38 Left nasal obstruction, bleeding (onset: 6MA), s/p ESS 진단은? |
| Discussion | Olfactory neuroblastoma 1) Introduction -Also called esthesioneuroblastoma -Rare malignant neuroectodermal tumor that arises from the superior nasal cavity -Tumor of neural crest origin that probably arise from basal cells of the olfactory epithelium 2) Imaging findings: • Dumbbell-shaped mass with “waist” at cribriform plate • Upper portion in anterior cranial fossa/ Lower portion in upper nasal cavity • Peripheral tumor cysts at intracranial tumor-brain margin: Highly suggestive of diagnosis • Intermediate SI on all imaging sequences, with the T2-weighted signal intensity being higher. • Avid homogeneous tumor enhancement/ heterogeneous enhancement in areas of necrosis 3) Olfactory neuroblastoma outside superior nasal cavity • Reported ectopic sites include the petrous apex, sphenoid sinus, maxillary sinus, nasopharynx, anterior ethmoids, inferior meatus of the nasal cavity, and floor of the nose, sellar.. • Ectopic cell rests as a result of impaired migration of olfactory placode neuronal cells/Accessory olfactory systems fails to degenerate • Transformation of pituitary epithelium into neuronal cells |
| Correct answer |
Correct AnswerSemi-Correct Answer |