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종결 Case No. 574 2020-12-01~2020-12-31
출제자 : 유인선 Hit : 613
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Period 2020-12-01~2020-12-31
Diagnosis Miller Fisher syndrome
Gender
  • M
  •  
  • F
Age 64
Clinical information M/64
C.C> dizziness, both eye gaze palsy (CN III, IV, VI palsies)-2-3DA
Discussion Miller Fisher syndrome
1) Introduction
-Also known as Miller Fisher variant of Guillain-Barre syndrome (GBS), an acute peripheral neuropathy that can develop after exposure to various viral, bacterial, and fungal pathogens.
-Accounts for 1-5% f GBS in Western countries, M:F=1:2 and preceded by an upper respiratory illness in most patients
-Often immune-mediated and associated with anti-GQ1b antibodies
-Symptom triad: ophthalmoplegia (CN III, IV, VI involvement), gait ataxia (cerebellar involvement), areflexia (lower motor neuron involvement)
2) Imaging findings: Abnormal gadolinium enhancement of cranial nerves with/without increased T2 signal and enlargement of nerves.
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