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종결 Case No. 561 2020-08-01~2020-08-31
출제자 : 강경미 Hit : 392
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Period 2020-08-01~2020-08-31
Diagnosis Osmotic demyelination syndrome
Gender
  • M
  •  
  • F
Age 42
Clinical information M/42
Altered mentality (1DA)
진단은?
Discussion • Acute demyelination w/o severe inflammation
• Rapid shifts in serum osmolality
• Biphasic: initial seizure or altered mentaility, second deterioration (2-3 days after normonatremia)
• Alcoholism, nutrition deficiency, etc
Imaging (1 or 2 weeks behind Sx): symmetric
• Central Pontine Myelinolysis, isolated CPM(50%)
• Extrapontine Myelinolysis, exclusive EPM (20-25%)
; BG, hemispheric WM > thalami, LGB, cerebellum (MCP), midbrain
• CPM+EPM: pathognomonic (30%)
• DWI: most sensitive, may enhance
Correct answer

Correct Answer

  • 문경일 전남대학교병원
  • 김현진 가톨릭대학교 서울성모병원
  • 김신영 양산부산대학교병원
  • 임현지 서울의료원
  • 이진영 ----
  • 최은지 서울아산병원
  • 윤선근 가톨릭대학교 성빈센트병원

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