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Case No. 550
2020-04-01~2020-04-30
출제자 : 정미선
Hit : 515
| Period | 2020-04-01~2020-04-30 |
|---|---|
| Diagnosis | Neurocandidiasis/ candida abscess (fungal abscess) |
| Gender |
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| Age | 42 |
| Clinical information | 42/M seizure, underlying DM and chronic renal disease 진단은? |
| Discussion | Neurocandidiasis - Most common nosocomial fungal infection, CNS involvement occur up to 52% of disseminated candidiasis. - Risk factors: prolonged broad spectrum antibiotics, DM, corticosteroids and immunosuppressive agents. - Candida has a predilection for the microcirculation and resulted in multiple cerebral micro-abscesses, leptomeningitis, vasculitis, mycotic aneurysms and infarction. # Image findings Micro-abscesses - Hallmark radiographic feature of neurocandidiasis - Less than 3 mm in size, multiple, and most commonly located at the gray-white matter junction, basal ganglia, and/or cerebellum - MR signal characteristics that are identical to other brain abscesses. - Small hemorrhagic components are also commonly observed. Leptomeningitis - Non-specific leptomeningeal enhancement without any specific distribution. |
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Correct AnswerSemi-Correct Answer |