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종결 Case No. 541 2020-01-01~2020-01-31
출제자 : 박지은 Hit : 613
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Period 2020-01-01~2020-01-31
Diagnosis Multinodular and vacuolating neuronal tumor (MVNT)
Gender
  • M
  •  
  • F
Age 52
Clinical information 건강검진에서 발견된 뇌종양 의심소견으로 내원한 52세 여자 환자이다. 1년전부터 두통이 심해져서 약으로 조절 중이라고 한다. 진단은?
Discussion 1. Multinodular and vacuolating neuronal tumor (MVNT) is a newly recognized cytoarchitectural pattern in the recently revised 2016 edition of the WHO classification of CNS tumors.
Radiologically, MVNTs appear as small 'bubbly' indolent subcortical tumors that sometimes present with seizures. These tumors have been most frequently identified in the temporal lobe, although that is likely to be due to that location being more likely to result in seizures than necessarily a predilection for that lobe

2. Radiologic finding
CT : Smaller lesions are difficult to identify, but if seen will appear as non-enhancing low attenuation lesions deep to the cortex in the subcortical white matter.
MRI : These tumors appear as a cluster of well circumscribed high T2 signal 'bubbles' located predominantly in the subcortical white matter, but can involve overlying cortex.
T1: hypointense to adjacent grey and white matter
T1 C+: usually no enhancement, some faint focal enhancement may be seen
T2: hyperintense to grey and white matter, almost as high as CSF
FLAIR: do not suppress

3. Treatment : if asymptomatic, be followed by imaging alone.
In symptomatic patients (epileptic) surgical resection often controls seizures.

Correct answer

Correct Answer

  • 이진영 ----
  • 박채정 연세의대 세브란스병원
  • 문성준 경북대학교병원
  • 김현진 서울아산병원

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