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Case No. 521
2019-07-01~2019-07-31
출제자 : 차지훈
Hit : 364
| Period | 2019-07-01~2019-07-31 |
|---|---|
| Diagnosis | hypereosinophilic syndrome |
| Gender |
|
| Age | 23 |
| Clinical information | M/23 C.C> leg weakness 진단은? |
| Discussion | hypereosinophilic syndrome Imaging findings - Young age - Multistage, multifocal borderzone infarctions - Intact large arteries - Endomyocardial fibrosis Review - Idiopathic hypereosinophilic syndrome (HES) - Blood eosinophilia ≥1500/mm3 for more than 6 months - lack of evidence for known causes of eosinophilia - presumptive signs of end-organ damage - Pathophysiology - Thromboembolic infarction Vascular endothelial toxicity of eosinophilic cells Eosinophilic involvement of cardiac endocardium, endomyocardial fibrosis Platelet activation and aggregation, defect in anticoagulation Borderzone vulnerable to embolic infarction due to delayed and incomplete clearance of microemboli |
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