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Case No. 519
2019-06-01~2019-06-30
출제자 : 이경식
Hit : 552
| Period | 2019-06-01~2019-06-30 |
|---|---|
| Diagnosis | Multinodular and vacuolating neuronal tumor (MVNT) |
| Gender |
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| Age | 55 |
| Clinical information | 55세 여자환자. 좌측 안면부 감각 이상으로 촬영한 Brain MRI이다. 진단은? |
| Discussion | Multinodular and vacuolating neuronal tumor (MVNT) newly recognized cytoarchitectural pattern in the recently revised 2016 edition of the WHO classification of CNS tumors Radiologically, MVNTs appear as small 'bubbly' indolent subcortical tumors Most frequently identified in the temporal lobe Sometimes present with seizures Although currently considered a tumor and a growth pattern of gangliocytomas (WHO grade I), MVNTs are closer to developmental abnormalities than true tumor Histopathologic hallmark : neuroepithelial cells with conspicuous stromal vacuolation arranged in nodules principally within the deep cortical ribbon and superficial subcortical white matter DDx. with DNET (dysembryoplastic neuroepithelial tumor) absence of cortical involvement and prominent mass effect intra- or perilesional tumor nodules |
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Correct Answer
Semi-Correct Answer |