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Weekly Case

종결 Case No. 512 2019-04-01~2019-04-30
출제자 : 정미선 Hit : 335
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Period 2019-04-01~2019-04-30
Diagnosis Neurosyphilis
Gender
  • M
  •  
  • F
Age 61
Clinical information 61세 남자
왼쪽 얼굴에 central type facial palsy와 both leg weakness가 2달 전부터 있었다.
진단은?
Discussion Neurosyphilis
1. Early neurosyphilis
Acute syphilitic meningitis
- Focal or diffuse leptomeningeal enhancement
- Gummas : small nodules adjacent to the meninges
- Meningomyelitis: m/c in thoracic spinal cord with or without involvement of the dorsal columns
Meningovascular syphilis
- Focal segmental vascular narrowing and ‘beading’ on MRA
- Cortical or subcortical infarction in any vascular territory
- Acute encephalitis : T2-weighted hyperintensities in medial temporal lobes  atrophic change
- Can be combined with the image findings of acute syphilitic meningitis.
Otosyphilis : Gummas may be seen in the internal auditory canal

2. Late neurosyphilis
General paresis: cerebral atrophy, both central and cortical atrophy
Tabes dorsalis: Atrophy and longitudinal T2 high signal change in the dorsal columns of the spinal cord
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