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Case No. 469
2018-01-01~2018-01-31
출제자 : 박지은
Hit : 298
| Period | 2018-01-01~2018-01-31 |
|---|---|
| Diagnosis | Hypoglycemic encephalopathy |
| Clinical information | 18/F Altered mentality. Underlying disease: hypopituitarism |
| Discussion | Pathophysiology- poorly understood 1) Energy failure : selective neuronal loss predominantly in the cerebral cortex, caudoputamen, and hippocampus vs. sparing cerebellum, brain stem, thalamus, and hypothalamus ( glucose transport ↑) 2) Excitotoxic edema : glutamate edema in glial cells and myelin sheaths -> reversible 3) Blood autoregulation References: 1) Ma JH et al. Neuroradiology 2009 Oct;51(10):641-9. MR imaging of hypoglycemic encephalopathy: lesion distribution and prognosis prediction by diffusion-weighted imaging 2) Witsch J et al. J Neurol. 2012 Oct;259(10):2172-81 Hypoglycemic encephalopathy: a case series and literature review on outcome determination. |
| Correct answer |
Correct AnswerSemi-Correct Answer |