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종결 Case No. 468 2018-01-01~2018-01-31
출제자 : 박지은 Hit : 232
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Period 2018-01-01~2018-01-31
Diagnosis radiation induced sarcoma (RIS)
Clinical information 24/F
Palpable mass at right auricular area.
1세 이전에 우안 retinoblastoma치료 후 얼굴이 비 대칭적으로 자란 과거력
Discussion
The generally accepted criteria of RIS proposed by Cahan and modified by Arlen et al are:
1. 1) treatment with therapeutic irradiation at least three years prior to development of sarcoma
2. 2) a sarcoma arising within the field of previous therapeutic irradiation
3. 3) differing histology between the sarcoma and the primary tumor that required radiotherapy

RIS constitutes 2.5–5.5% of all sarcomas
Post-radiotherapy 10-year cumulative risk: 0.03–0.8%
Median interval between 10 and 20 years
Prognosis: poor compared to other sarcomas
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  • 이지예 울산의대 서울아산병원

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