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종결 Case No. 454 2017-08-01~2017-08-31
출제자 : 강경미 Hit : 298
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Period 2017-08-01~2017-08-31
Diagnosis Pituitary siderosis
Clinical information F/27
Amenorrhea (6MA)
진단은?
Discussion > pituitary siderosis
• Iron overload (hemochromatosis), such as multiple transfusion
• Tissue accumulation in the liver, pituitary gland, and other organs
• Anterior pituitary gland is a common site for iron deposition
• Increased iron concentrations have a cytotoxic effect leading to cell death and organ dysfunction.
• Hypogonadism, commonest clinical manifestation
• T2WI show a hypointense anterior pituitary gland
• Treated with iron chelation drugs
• Monitoring of the iron content by serum ferritin
• index of total body iron load
Reference>
Pediatr Radiol 2005; 35; 1045–1055
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