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종결 Case No. 389 2015-11-01~2015-11-30
출제자 : 유인선 Hit : 321
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Period 2015-11-01~2015-11-30
Diagnosis Tb granuloma
Clinical information M/67
C.C> 일주일전 시작된 gait disturbance
Discussion * CNS tuberculosis is almost always secondary
-tuberculous meningitis
-localized parenchymal infection (tuberculous granuloma/tuberculoma (common), Tb abscess (rare))
* Tuberculoma:
-noncaseating, caseating with solid center or caseating with necrotic center
-hematogenous spread or extension of meningitis into parenchyma via cortical veins or small perforators
-Typically parenchymal (supratentorial (m/c), infratentorial (rare)), dural tuberculomas may occur

* Imaging findings of tuberculous granuloma (tuberculoma)
-CT
Hypo to hyperdense round or lobulated nodule/mass with moderate to marked edema
Ca++ uncommon (~20%)
Solid or ring enhancement
-MR
Noncaseating granuloma: hyperintense on T1, hypointense to brain on T2, nodular homogeneous enhancement
Caseating granuloma: solid center, hypointense or isointense on T1 and hypointense on T2; necrotic center, central hypointensity on T1 and hyperintensity on T2, may have hyperintense rim (paramagnetic material) on T1, peripheral rim enhancement
Surrounding edema, common
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  • 김정윤 한림대학교 강남성심병원

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