| Period | 2015-02-02~2015-02-28 |
|---|---|
| Diagnosis | Chordoid Glioma |
| Clinical information | 61/ F CC: Headache Onset: 1 month ago |
| Discussion | Chordoid Glioma Rare adult tumor 1% of all glioma. Middle-aged adults(35-60 years old) 2:1 F:M ratio. WHO grade II neoplasm Anterior aspect of the 3rd ventricle adjacent to the lamina terminalis Etiology Unclear Origin from the lamina terminalis of the third ventricle suggest an ependymal histogenesis Chordoid Glioma Presentation Headache, nausea, memory impairment Visual field deficit Endocrine disturbance(10-15%) Treatment Frequently attached to the hypothalamus and floor of the third ventricle, resection is often subtotal Hypothalamic dysfunction with diabetes insipidus and obesity Imaging Well-dermarcated ovoid masses Confined to the third ventricle Clearly separate from the pituitary gland and infundibulum Often abut and may superficially adhere to the hypothalamus CT Findings Moderately hyperdense Strong, homogeneous enhancement Calcification have been reported MR Findings Sagittal MR ○ clearly separated from the pituitary gland and infundibular stalk T1/T2 isointense Strong uniform enhancement Intratumoral cysts(25%) Hemorrhage (rare) References 1. Osborn Brain, Imaging, Pathology, And Anatomy, Anne G. Osborn, AMYRSYS 2. Masses and Malformations of the Third Ventricle: Normal Anatomic Relationships and Differential Diagnoses RadioGraphics 2011; 31:1889–1905 3. Chordoid Glioma: A Neoplasm Unique to the Hypothalamus and Anterior Third Ventricle AJNR Am J Neuroradiol 22:464–469, March 2001 |
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Correct AnswerSemi-Correct Answer |