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종결 Case No. 362 2015-02-02~2015-02-28
출제자 : 최진우 Hit : 312
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Period 2015-02-02~2015-02-28
Diagnosis Chordoid Glioma
Clinical information 61/ F
CC: Headache
Onset: 1 month ago
Discussion Chordoid Glioma
 Rare adult tumor
 1% of all glioma.
 Middle-aged adults(35-60 years old)
 2:1 F:M ratio.
 WHO grade II neoplasm
 Anterior aspect of the 3rd ventricle adjacent to the lamina terminalis
 Etiology
 Unclear
 Origin from the lamina terminalis of the third ventricle suggest an ependymal histogenesis
 Chordoid Glioma
 Presentation
 Headache, nausea, memory impairment
 Visual field deficit
 Endocrine disturbance(10-15%)
 Treatment
 Frequently attached to the hypothalamus and floor of the third ventricle, resection is often subtotal
 Hypothalamic dysfunction with diabetes insipidus and obesity
 Imaging
 Well-dermarcated ovoid masses
 Confined to the third ventricle
 Clearly separate from the pituitary gland and infundibulum
 Often abut and may superficially adhere to the hypothalamus
 CT Findings
 Moderately hyperdense
 Strong, homogeneous enhancement
 Calcification have been reported
 MR Findings
 Sagittal MR
○ clearly separated from the pituitary gland and infundibular stalk
 T1/T2 isointense
 Strong uniform enhancement
 Intratumoral cysts(25%)
 Hemorrhage (rare)
 References
1. Osborn Brain, Imaging, Pathology, And Anatomy, Anne G. Osborn, AMYRSYS
2. Masses and Malformations of the Third Ventricle: Normal Anatomic Relationships and Differential Diagnoses RadioGraphics 2011; 31:1889–1905
3. Chordoid Glioma: A Neoplasm Unique to the Hypothalamus and Anterior Third Ventricle
AJNR Am J Neuroradiol 22:464–469, March 2001

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