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종결 Case No. 343 2014-07-01~2014-07-31
출제자 : 안성준 Hit : 388
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Period 2014-07-01~2014-07-31
Diagnosis Neurosyphilis
Clinical information M/37
Fever, 의식저하, Eyeball deviation, 기억력 감소
진단은?
Discussion  Refers to an infection of the brain and spinal cord caused by a microorganism, a spirochete named Treponema pallidum
 Transmitted during sexual intercourse
 The infection can occur at any stage of the disease process
- one third of patients in the tertiary stage develop
 Divided into asymptomatic neurosyphilis, acute syphilitic meningitis, cerebrovascular neurosyphilis, the encephalitis or general paresis
 Imaging findings of neurosyphilis
- include cerebral infarctions (typically lacunar or middle cerebral artery in
distribution)
- or nonspecific white matter lesions in meningovascular syphilis,
- cerebral gummas
- arteritis
- cortical atrophy has been reported in patients with general paresis
- Mesial temporal lobe abnormality
 In the present study, a MRI revealed high signal changes in the bilateral mesial temporal lobes, including both the hippocampi and amygdalae
 Differential diagnosis.
- HSV encephalitis
- Limbic encephalitis.

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Semi-Correct Answer

  • 이광진 인제의대 일산백병원
  • 김승수 순천향대학교 천안병원
  • 손범석 연세의대 세브란스병원
  • 유성혜 고려대학교 안암병원
  • 강건우 고려대학교 안암병원
  • 서종현 울산의대 서울아산병원
  • 윤성종 강동경희대학교병원
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