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종결 Case No. 317 2013-10-01~2013-10-31
출제자 : 김대윤 Hit : 357
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Period 2013-10-01~2013-10-31
Diagnosis eosinophilic otitis media
Clinical information F/17

C.C : Both thick otorrhea from 3 years ago
Total IgE : 1116 KU/L (Normal : <100)
진단은?
Discussion F/17

C.C : Both thick otorrhea from 3 years ago
Total IgE : 1116 KU/L (Normal : <100)

Past history:
S/P pressure equilibrium tube, right, 1 year ago
Known allergic asthma

Answer : eosinophilic otitis media

설명 및 리뷰
Middle ear cavity에 soft tissue 또는 fluid가 있고 동반되어 rhinosinusitis 가 같이 있다. 또한 양측 E-tube가 patent하다.
Temporal bone CT상 middle ear cavity 에 soft tissue lesion and fluid가 있어 일반적인 acute or chronic otomastoiditis생각할 수 있다. 그러나, IgE가 올라가는 등의 천식환자에서 otorrhea 가 thick discharge를 보일 때, 임상적으로 eosinophilic otomastoiditis를 의심해 볼 수 있다. 이 때 Patent E-tube, Smooth and soft-tissue bulging from the inflamed middle ear cavity with bilateral involvement, Bilateral paranasal sinusitis 가 보이면, CT에서도 eosinophilic otomastoiditis를 생각할수 있는데, 특히 일반적인 COM의 기전과 달리 E-tube가 patent한 경우, 이 exudate가 drainage 장애에 의한 것이 아니고, inflamed muscosa에서 흘러나온 것을 시사하는 것으로 eosinophic otomastoiditis 를 시사하는 중요 소견으로 알려져 있다.

Review
Eosinophilic otitis media
 Relatively rare, intractable disease characterized by the presence of a highly viscous yellow effusion with extensive accumulation of eosinophils in the middle ear
 On physical examination, most EOM patients show a patulous Eustachian tube rather than tubal stenosis, which is different from OME or COM.
 T helper type 2-dominant predisposition, such as bronchial asthma, an antigenic material may easily invade via a patulous Eustachian tube and stimulate inflammatory cells.
 occurs mainly in patients with bronchial asthma and is resistant to conventional treatments for otitis media
 Treatment: systemic or topical glucocorticoid is believed to be the most effective treatment for EOM

 CT finding
might be similar to COM, with heterogeneous soft tissue within the middle ear and mastoid, with or without minimal erosion of the ossicles
DDx point :
1. Smooth, soft-tissue bulging from the inflamed middle ear cavity
2. Bilateral paranasal sinusitis
3. Clearly visible tubal Eustachian tubal lumina

 Reference
Won Jung Chung MD et al. Eosinophilic Otitis Media: CT and MRI Findings and Literature Review. Korean J Radiol. 2012 May-Jun; 13(3): 363–367.
 Iino Y, Tomioka, et al. Diagnostic criteria of eosinophilic otitis media, a newly recognized middle ear disease. Auris Nasus Larynx. 2011;38:456–461.

Correct answer

Correct Answer

  • 백혜진 ----
  • 윤성종 강동경희대학교병원
  • 서종현 울산의대 서울아산병원
  • 김현수 성균관대학교 삼성서울병원
  • 김미미 ----

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