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Case No. 286
2012-11-01~2012-11-30
출제자 : 차지훈
Hit : 484
| Period | 2012-11-01~2012-11-30 |
|---|---|
| Diagnosis | Xanthomatous hypophysitis |
| Clinical information | F/36, 두통, 구토, 발열 진단은? |
| Discussion | Xanthomatous hypophysitis Primary (autoimmune) hypophysitis Focal or diffuse inflammatory infiltration and destruction of the pituitary gland causing varying degrees of endocrine dysfunction. Three categories: lymphocytic, granulomatous and xanthomatous (XH). Infiltration of mixed inflammatory cells, which consist of foamy cells (xanthomatous cell), plasma cells and small mature lymphocytes, in the anterior pituitary gland. XH has been shown to have a predilection for young women Radiologic findings Central cystic lesion or necrosis Inflammation is predominant in the anterior pituitary lobe Transsphenoidal surgery is both diagnostic and therapeutic. Steroid therapy seems less effective in XH compared to other kinds of primary hypophysitis. References Xanthomatous hypophysitis. J Clin Neurosci. 2012 Jun 7. [Epub ahead of print] Xanthomatous hypophysitis mimicking a pituitary adenoma: case report and review of the literature. J Oncol. 2010;2010:195323. |
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