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Case No. 274
2012-06-01~2012-06-30
출제자 : 김진아
Hit : 479
| Period | 2012-06-01~2012-06-30 |
|---|---|
| Diagnosis | Lymphoma in a patient with AIDS |
| Clinical information | 24세 남자, general weakness and fever for 3 days 진단은? |
| Discussion | Lymphoma in a patient with AIDS Immunocompromised patients are at increased risk for developing primary CNS lymphoma. Nearly 6% of the AIDS population will be afflicted with an intracranial lymphoma. The age at presentation is earlier (fourth decade) in immunocompromised patients than in the immunocompetent, but the cell type (B cell) and presenting signs and symptoms are similar. Brain MR imaging reveals a higher frequency of multiple lesions and more often displays irregular margins, heterogeneity, and ring enhancement. In the immunocompromised population, an important dilemma is the difficulty in distinguishing primary CNS lymphoma from the more common cerebral toxoplasmosis using CT and MR imaging, because both entities can present with multiple ring-enhancing lesions. References 1. Thurnher MM, Rieger A, Kleibl-Popov C, Settinek U, Henk C, Haberler C, Schindler E. Primary central nervous system lymphoma in AIDS: a wider spectrum of CT and MRI findings. Neuroradiology 2001;43:29–35. 2. Slone HW, Blake JJ, Shah R, Guttikonda S, Bourekas EC. CT and MR findings of intracranial lymphoma. AJR 2005;184:1679–85. |
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