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종결 Case No. 242 2011-06-01~2011-06-30
출제자 : 이영흔 Hit : 378
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Period 2011-06-01~2011-06-30
Diagnosis
Clinical information M/64
C.C: disorientation
치료전(상좌, 상우) 치료후(하좌, 하우)
Discussion 정답: Wernicke encephalopathy
DWI에서 both medial thalamus, periaqueductal region에서 high SI-->
Thiamine IV infusion support후 사라짐.

해설
Neurologic disorder caused by thiamine deficiency
Clinical features:
ataxia, hypomnesia, and global confusion
Mostly background of alcohol abuse
Pathology during acute phase
variable degrees of necrosis, vascular proliferation, astroglial and microglial proliferation, and petechial hemorrhages in the medial thalami, mammillary bodies, periaqueduct, floor of the fourth ventricle, and superior vermis
MR imaging findings
FLAIR/ T2WI: increased SI in periaqueduct area and bilateral medial thalami
atrophy of the mammillary bodies and cerebellar vermis
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