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종결 Case No. 241 2011-05-01~2011-05-31
출제자 : 최승홍 Hit : 484
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Period 2011-05-01~2011-05-31
Diagnosis
Clinical information F/37
C.C: 양팔마비, loss of consciousness (6 MA)
Discussion Answer: Atypical extraventricular neurocytoma


Definition
Neurocyte-containing neuronal or glioneuronal tumors that are geographycally remote from the region of the foramen of Monro
IHC
Diffuse synaptophysin (+) in cytoplasm and neuropil
NeuN (+) in nucleus
Deletion of chromosome 1p and 19q
24% 1p19q co-deletion and 10% 1p loss
Atypical histologic features (Brain Pathol. 2009)
Atypical EVN
Ki-67 LI >2% with/without anaplastic features viz. focal necrosis and vascular proliferation
Short recurrent free survival
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