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종결 Case No. 183 0000-00-00~0000-00-00
출제자 : 관리자 Hit : 313
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Period 0000-00-00~0000-00-00
Diagnosis
Clinical information 58세 여자, 일 년간의 left facial pain (V1-3) with hypothesia, 일 개월간의 좌측 visual acuity감소로 내원. 당뇨병이 있고, 18개월 전 신장 이식 받음.
Discussion Aspergillosis

Cerebral involvement by Aspergillus results from hematogenous spread from a pulmonary focus, or the fungus may also directly invade the brain via the sinus
The signs and symptoms include a change in mental status, hemiparesis, dysarthria, lethargy, and seizures, with or without fever
Involvement of the skull base and orbit leads to visual disturbance and cranial nerve palsies

Imaging patterns for cerebral aspergillosis
(a) Multiple cortical and subcortical regions of low attenuation on CT images, with T2 hyperintensity seen in corresponding areas on MR images
(b) Multiple ring-enhancing lesions
(c) Dural enhancement adjacent to enhancing lesions of the paranasal sinuses or calvaria
The presence of hemorrhage associated with the lesions and intraparenchymal hemorrhage in an immunocompromised patient should cause one to consider the possibility of aspergillosis


RadioGraphics 2008; 28:2033?058
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