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종결 Case No. 172 0000-00-00~0000-00-00
출제자 : 관리자 Hit : 323
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Period 0000-00-00~0000-00-00
Diagnosis
Clinical information 59세 남자, left side motor weakness, dysarthria로 내원
Discussion CNS involvement of Behcet?disease

Imaging findings
On T2WI, multifocal high signal intensity areas involving both periventricular white matter, posterior limbs of internal capsule, pons. They are relatively hypointense on T1WI with subtle parenchymal enhancement

Review
Neurobehcet disease
CNS involvement of Behcet?disease
Pathophysiology: small vessel vasculitis (CNS intraaxial veins; predominantly involved)
Location:
m/c ; brainstem, especially around the cerebral peduncles and the pons, thalamus and basal ganglia
similar foci in the cerebral hemispheres
MR:
small foci of high signal intensity on T2WI
iso- or hypointense relative on T1WI
circular, linear, crescent-shaped, or irregular
Non-parenchynmal involvement:
Venous Thrombosis: superior sagittal sinus, transverse sinus, deep cerebral veins, cavernous sinuses
Arterial Aneurysm
Arterial Occlusion or Dissection
Aseptic meningitis
Differential diagnosis
ADEM: Multifocal subcortical hyperintense foci on T2WI/ cerebral or cerebellar cortices, deep WM, BS
HSV encephalitis: Limbic system (temporal lobe, insular ctx, cingulate gyri, subfrontal ctx)
Behcet disease: central part of the pons/corticospinal tract, basal ganglia, thalamus, and internal capsule
REFERENCE
Radiologic and Clinical Findings of Beh?t Disease: Comprehensive Review of Multisystemic Involvement RadioGraphics 2008, 10.1148/r.e31
MR Features of Diseases Involving Bilateral Middle Cerebellar Peduncles, AJNR Am J Neuroradiol 24:1946?954, November/December 2003
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