HOME > Weekly Case > Weekly Case
Weekly Case
종결
Case No. 162
0000-00-00~0000-00-00
출제자 : 관리자
Hit : 377
| Period | 0000-00-00~0000-00-00 |
|---|---|
| Diagnosis | |
| Clinical information | 49세 여자. 15일전 발생한 어지러움으로 내원 3년간 고혈압으로 투약중 |
| Discussion | Lymphomatosis cerebri (T-cell lymphoma) 감별진단: 1) toxic metabolic demyelinating Dz, 2) MS, 3) tumor such as gliomatosis cerebri, lymphomatous cerebri, 4) leukoencephalopathy etc Review: Lymphomatosis cerebri (LC): Very rarely, PCNSL lymphoma manifests as a diffuse infiltrating disease involving the whole neuraxis which is then referred to as LC. Clinically, LC typically presents with a rapidly progressive dementia. Typical MRI features of LC are diffuse leukoencephalopathy bilaterally in the hemispheres on T2 weighted images, reflecting widespread infiltration of the cerebral white matter by lymphomatous cells but no contrast enhancement. Brainstem and basal ganglia involvement was also observed. Mimics other white matter disorders, including Binswanger’s disease, metabolic leukoencephalopathies, and infectious or autoimmune diseases primarily involving the white matter. Reference: Dementia and leukoencephalopathy due to lymphomatosis cerebri, J. Neurol. Neurosurg. Psychiatry 2007;78;777-778 Primary CNS lymphoma of T-cell origin, J Clin Oncol 2005;23:2233-2239 Proton magnetic resonance spectroscopy in immunocompetent patients with primary central nervous system lymphoma, Journal of neuro-Oncology 2005;71:173-180 |
| Correct answer |
Correct AnswerSemi-Correct Answer |