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종결 Case No. 100 0000-00-00~0000-00-00
출제자 : 관리자 Hit : 413
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Period 0000-00-00~0000-00-00
Diagnosis
Clinical information 30세 여자 두통으로 영상 시행
Discussion [정답] Glomus Jugulare Paraganglioma

1) Clinical
Paraganglioma involving jugular bulb and skull base, along Jacobson's nerve
Most common tumor in jugular fossa with intracranial extension
Origin: adventitia of jugular bulb
Predominant symptoms: tinnitus, hearing loss, cranial nerve palsy

2) Imaging
High resolution CT with bone setting: most helpful imaging study.
CT Findings:
◦ erosion and enlargement of the jugular fossa
◦ erosion of the floor of the middle ear, ossicle erosion.
◦ As the tumour enlarges
-> posteroinferior side of the petrous pyramid erosion,
-> eventually involving the occipital bone, hypoglossal canal, foramen
magnum
-> extension into the posterior fossa extradurally
-> inferior extension along or within the internal jugular vein

MRI: "salt and pepper" appearance (multiple tumor vessels)
Angio: hypervascular mass; invasion/obstruction of the jugular bulb by thrombus/tumor; AV shunting
3) Natural Hx
◦ slow growing and rare metastasis.
◦ malignant transformation with mets to regional nodes (2-4%)
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